Friday, May 27

Surprise: anti-inflammatories increase chronic pain | Digital Trends Spanish


An investigation of the McGill Universitydiscovered that taking anti-inflammatories when acute pain is treated, it can be counterproductive in the future, since it would be associated with chronic pain.

To achieve these results, patients with acute low back pain were taken as a sample.

Co-lead author Luda Diatchenko detailed what some of the findings were from looking at anti-inflammatories to treat this problem.

“By analyzing the genes of people who suffer from low back pain, we observed active changes in the genes over time in people whose pain disappeared. Changes in blood cells and their activity seemed to be the most important factor, especially in cells called neutrophils.”

This was unexpected, as anti-inflammatory medications are routinely used to treat lower back pain, and years of evidence have established that they help reduce pain. But this initial finding suggested that suppressing an early inflammatory response to pain might be doing something to increase the risk of developing chronic pain.

“For many decades it has been standard medical practice to treat pain with anti-inflammatory medications. But we found that this short-term fix could lead to long-term problems,” he says. Jeffrey Mogilprofessor in the Department of Psychology at McGill University and EP Taylor Chair in Pain Studies.

“Our findings suggest that it may be time to reconsider how we treat acute pain. Fortunately, pain can be killed in other ways that don’t involve interfering with inflammation,” says Massimo Allegri, a physician at Monza Hospital Polyclinic in Italy and Ensemble Hospitalier de la Cote in Switzerland.

One of the solutions would be the use of analgesics, but not medications that reduce inflammation, since the active biological process of pain must be allowed to dissolve in its normal curve.

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